The Business Case for Precision Recruitment

Aug 25, 2026

Event Overview:

Clinical trial success depends on more than recruiting enough participants. The scientific relevance of the study population can have a significant influence on variability, treatment effect detection, data quality, timelines and overall research ROI.

Vedic Lifesciences hosted The Business Case for Precision Recruitment, a scientific webinar that explored how phenotype-guided participant selection can help improve clinical trial design and recruitment outcomes. Led by Dr. Mark JS Miller and Dr. Sachin Dighe, the webinar examined an important question for clinical research: Are clinical trials recruiting participants who are biologically capable of responding to the intervention?

The discussion explored how heterogeneous study populations can increase baseline variability and dilute treatment effects when responders and biological non-responders are analyzed together. This can make statistical significance more difficult to achieve, potentially requiring larger sample sizes and increasing the cost of clinical research.

The webinar introduced Precision Recruitment as a phenotype-guided framework designed to reduce baseline variability, improve responder probability and potentially maximize clinical trial ROI.

Rather than asking only whether a participant meets protocol eligibility criteria, the discussion examined a more fundamental question: Is the participant biologically relevant for the intervention?

The webinar also explored practical applications of precision recruitment in nutraceutical clinical trials, regulatory perspectives on population enrichment and examples demonstrating the importance of biologically relevant participant selection.

Event Overview:

The webinar introduced Precision Recruitment as a phenotype-guided framework designed to reduce baseline variability, improve responder probability and potentially maximize clinical trial ROI.

Event Overview:

The webinar introduced Precision Recruitment as a phenotype-guided framework designed to reduce baseline variability, improve responder probability and potentially maximize clinical trial ROI.

Key Discussion Points

Understanding Precision Recruitment

What precision recruitment means in modern clinical research
Why traditional recruitment strategies often fall short

Improving Recruitment Performance

Identifying the right participants from the beginning
Reducing screen failures and recruitment bottlenecks
Increasing participant retention throughout the study

Business Impact

Cost savings through optimized recruitment
Faster enrollment and reduced study timelines
Improving study quality and regulatory confidence

Practical Applications

Precision recruitment in nutraceutical clinical trials
Real-world experiences and practical recommendations

Speakers

Dr. Mark Miller

Dr. Mark Miller is a globally recognized expert in clinical research, nutraceutical science and evidence-based product development. Throughout his career, he has worked with leading ingredient suppliers, dietary supplement companies and health brands to develop scientifically rigorous research programs that support product differentiation and commercial success.

His expertise spans clinical trial design, regulatory strategy, scientific substantiation, publication planning and translating research findings into meaningful business outcomes. Dr. Miller is widely respected for helping organizations bridge the gap between scientific evidence and market success.

Dr. Sachin Dighe

Dr. Sachin brings over two decades of experience across medical practice, nutraceutical innovation and clinical research to shape high-impact, MOA-driven study strategies. A medical doctor trained in Ayurveda and having worked with global leaders, his core strengths include clinical trial strategy, operations and regulatory medical writing, with a specialised focus on claim substantiation. At Vedic Lifesciences, he leads the claim substantiation function, helping brands translate science into credible, differentiated and compliant product claims.

About Vedic Lifesciences

Vedic Lifesciences is a specialist Contract Research Organization (CRO) with more than 25 years of experience in clinical research and evidence generation. The organization works across nutraceuticals, pharmaceuticals, medical devices, functional foods, probiotics, herbal products and consumer healthcare, supporting sponsors with scientifically driven clinical research solutions.

Vedic's capabilities span human clinical trials, preclinical research, biostatistics, regulatory writing, real-world evidence, post-marketing research and claim substantiation.

Its experience in nutraceutical and consumer health research enables sponsors to develop clinical evidence aligned with scientific objectives, product claims and regulatory requirements.

About Vedic Lifesciences

Vedic's capabilities span human clinical trials, preclinical research, biostatistics, regulatory writing, real-world evidence, post-marketing research and claim substantiation.

Its experience in nutraceutical and consumer health research enables sponsors to develop clinical evidence aligned with scientific objectives, product claims and regulatory requirements.

About Vedic Lifesciences

Vedic's capabilities span human clinical trials, preclinical research, biostatistics, regulatory writing, real-world evidence, post-marketing research and claim substantiation.

Its experience in nutraceutical and consumer health research enables sponsors to develop clinical evidence aligned with scientific objectives, product claims and regulatory requirements.

What is precision recruitment in clinical trials?

Precision recruitment is a participant selection approach that considers biological and phenotypic characteristics in addition to conventional eligibility criteria. The objective is to identify participants whose biology is relevant to the mechanism of action and scientific objective of the intervention.