Vedic Lifesciences Capabilities
Dive into our Key-focus health areas and learn about the gold standard tools used – leverage your next clinical trial
Gut & Digestive Health
Trending claim areas: Irritable Bowel Syndrome (IBS), Constipation, Diarrhoea, Antibiotics Associated Diarrhoea (AAD), Small intestinal bacterial overgrowth (SIBO), Dysphagia, eating disorders, Gut Permeability.
Tools: IBS-Symptom Severity Scale, Pain-Numeric Rating Scale (NRS), Gastrointestinal Quality of Life Index (GIQLI), Bristol Stool Form Scale, Gastrointestinal Symptom Rating Scale (GSRS), Patient Assessment of Constipation QoL (PAC-QoL), Complete Spontaneous Bowel Moments, Three-Factor Eating Questionnaire-R18 (TFEQ-R18). Participant Assessment of Constipation Symptoms (PAC SYM)
Biomarkers:
Hydrogen Breath Test, Mannitol-Lactulose Test, Short Chain Fatty Acids (SCFA), Fecal Calprotectin, Microbiome Diversity – 16S rRNA sequencing, Next Gen Sequencing, Lipopolysaccharides (LPS).
Immunity, Cold & Flu
Trending claim areas: Immunity Boosting, Sick Days, Seasonal allergies, Symptoms relief – Peak flow lung function in Asthma, URTI, Vaccine adjuvants, long haul, work productivity, lung & respiratory capacity, quick onset immune-modulator, general well-being, Total Antioxidant Capacity.
Tools: No. of sick days, No. of episodes of URTI and allergies, Pulmonary Function Test Questionnaires like WURSS -21, VAS, and Leicester cough questionnaire. Immune Status Questionnaire (ISQ), Fatigue Severity Scale (FSS)
Biomarkers: Inflammatory Biomarkers like IL-6, NK Cell levels, IgG, IL-10, IL-2, TNF-alpha, CRP, RT-PCR, D-Dimer, Urinary eosinophil protein X, CBC, ESR, FRAP Assay, Rapid Antigen Test.
Bone & Joint Health
Trending claim areas: Joint comfort, flexibility & stiffness, knee discomfort, osteoarthritis, Range of motion, osteoporosis, postmenopausal joint discomfort, sarcopenia, low back pain.
Tools: WOMAC for Physical function, Stiffness, Mobility & Pain, Pain Visual Analog Scale (VAS), Knee Injury & OA Outcome Scale (KOOS), Lequesne Index, EQ-5D-5L, DEXA Scan (Bone Density), ROM, Naughton protocol, 6-minute walk test, Goniometry, Radiographic imaging.
Biomarkers: Urinary CTX-I, urinary CTX-II, serum COMP, BALP, osteocalcin, Osteoprotegrin, P1NP, Osteopontin, Bone mineral density, Vit D, PTH, Procollagen Type I C-Terminal Propeptide (C1NP), Human Tartrate Resistant Acid Phosphatase (TRAP), DPD (Urine marker), Human Cross Linked N-Telopeptide of Type I Collagen – NTx (Urine marker).
Cognitive Support
Trending claim areas: Alertness, Focus, Attention, Memory, Mood profile, Stress & anxiety, fatigue, E-gaming, Reaction time, Hypo-pituitary Axis (HPA) support, hangover remedy.
Tools: Profile of Moods States (POMS), Perceived Stress Scale, GAD-7, Depression, Anxiety and Stress Scale – 21 (DASS-21), Stroop test, TMT, Paired Associate Learning (PAL) Delayed Matching to Sample (DMS) Spatial Span (SSP) Emotion Recognition Test (ERT), State-Trait Anxiety Inventory (STAI), Attention Network Test, CANTAB, Cogtest, Mini-Mental State Examination, Magnetic Resonance Imaging (MRI), Hangover Symptom Scale Questionnaire, Acute Hangover Scale (AHS), Acute Hangover Severity Scale (AHSS). Figner Tapping Test (FTT), Four Part Continous Performance Test (FP CPT), Sam Perelli Fatigue Scale (SPFS)
Biomarkers: Serotonin, alpha-amylase, adrenocorticotrophic hormone, Cortisol, Serum levels of neurofilament light (NFL), amyloid beta-42, BDNF, Cortical perfusion, cytokine IL-17, Morning IL-6 levels, blood alcohol concentration (BrAC).
Complete Blood Count (CBC), Liver Function Test (LFT), Kidney Function Test (KFT)
Sleep
Trending claim areas: Sleep quality, Sleep duration, Stages of Sleep, Anxiety, Sleep patterns, Sleep initiation, morning freshness.
Tools: Insomnia Severity Index questionnaire (ISI), Restorative Sleep Questionnaire (RSQ), Pittsburg Sleep Quality Index (PSQI), Polysomnography, electroencephalogram (EEG), Computerised Assessments, Leeds Sleep Evaluation Questionnaire (LSEQ) Score, sleep latency (SL), total sleep time (TST), distribution of sleep and awake periods throughout the day (DSW), actigraphy (sleep tracker devices), Epworth Sleepiness Scale (ESS). Restorative Sleep Questionnaire (RSQ-S), Stat Trait Anxiety Inventory (STAI – AD)
Biomarkers: Melatonin, cortisol (morning).
Metabolic: Weight Management / Loss
Trending claim areas: Appetite-suppressant, Metabolic rate, BMI reduction, obesity, Hyperlipidemia, weight maintenance, waist inches loss, Total fat % decrease, Android & Gynecoid type fat content.
Tools: Waist-to-hip ratio, BMI, DEXA, MRI, Relevant QoL Questionnaires: Obesity and Weight-Loss Quality of Life Instrument (OWLQOL) & the Weight-Related Symptom Measure (WRSM), The Impact of Weight on Quality of Life-Lite (IWQOL-Lite), Physical activity, Appetite and Diet Assessment Tool (ADAT), electronic diary for diet assessment.
Biomarkers: Ghrelin Leptin levels, adiponectin, Neuropeptide Y, MCP-1.
Metabolic: Blood Sugar Maintenance
Trending claim areas: Glycemic control, Insulin sensitivity, Diabetic Neuropathy, Meal Replacement Therapy.
Tools: Glucose tolerance test, Nerve Conduction Velocity (NCV) test, neuropathy total symptom score 6 questionnaires (NTSS-6), QUICKI, HOMA-Index, Euglycemic Clamp, Pulse Wave Velocity / Reactive Hyperemia Index.
Biomarkers: HbA1c, Fasting Blood Sugar (FBS), Homeostatic Model Assessment of Insulin Resistance (HOMA – IR), Continuous Blood Glucose Monitoring, Post-Prandial dysmetabolism with Lipidomic profile, human Islet amyloid polypeptide (hIAPP) mAB. Oral Glucose Tolerance Test
Mother & Baby
Trending claim areas: Pregnancy-induced anemia, Insulin resistance, Gestational diabetes, Infantile colic, Antibiotic- Associated Diarrhea, Malnutrition, infant developmental disorders, stunted growth, LRTI and URTI in infants.
Tools: Bristol Stool Scale, No. & Duration of symptoms, the severity of symptoms, Bayley III, Wechsler Intelligence Scale for Children (WISC), Behavioral questionnaire, Maternal diet (FFQ), Infant weight, height, & diet, Parenting Stress Index, Edinburgh Postnatal Depression Scale, Barr’s Diary. Maternal Postpartum MAPP – QOL, World Health Organisation Quality of Life Brief Questionnaire WHOQOL – BREF
Biomarkers: Ferritin levels, IL-2, Saliva proteins, Blood Urea Nitrogen (BUN), Metabolomics (serum and urine samples
Men’s Health
Trending claim areas: Testosterone boosting, Healthy libido, better erection, better semen volume & quality, sperm mobility, Benign Prostatic Hyperplasia (BPH) management, Fertility, Sexual Satisfaction.
Tools: Aging Male Symptom Scale, Quality of Life Questionnaires, Self-Esteem And Relationship Questionnaire (SEAR), VAS, International Index of Erectile Function (IIEF).
Biomarkers: Testosterone levels, Sperm count, Sperm viability, HbA1c, Lipid profile, Thyroid.
Eye Health
Trending claim areas: Digital eye strain, Dry eyes, Computer Vision Syndrome, Macular degeneration, Kids’eye study.
Tools: Computer Vision Syndrome Questionnaire, Visual Acuity, Asthenopia Visual Fatigue Likert Scale, Schirmer test, Tear break up time, Ocular surface, tear osmolarity, Non-invasive tear breakup time, Dry Eye Syndrome Questionnaire, Ocular Computerized Tomography (OCT), Neovascularization, Macular Pigment Optical Density (MPOD). Ocular Surface Disease Index – OSDI, EAPIX, Flurescein Staining, Salicylic Acid
Sports Nutrition
Trending claim areas: Muscle recovery, Muscle gain (lean muscle mass, android & gynecoid fat, total fat % decrease), muscle strength, Aerobic fitness, Time to Exhaustion, Sports Injury recovery period, hydration levels, Basal Metabolic Rate (BMR), Performance improvement, Pre-workout & post-work- out strength, endurance.
Tools: VO2 MAX (Bruce Protocol), Resting Energy Expenditure (REE), Resting metabolic rate, 1RM leg press, bench press and Dynamometer, fatigue index
Miscellaneous
Trending claim areas: Urinary incontinence, Heart health (Blood pressure, Cholesterol, Arterial Stiffness, Hypertension), Non-Alcoholic Fatty Liver Disorder (NAFLD).
Tools: Blood Pressure Monitoring, Flow-mediated Dilation (FMD), FIBROSCAN, Endothelial Function Management.
Biomarkers: Lipid Profiling, ALT, AST, Serum creatinine, Electrolyte levels, Calcium levels.
Women’s Health
Trending claim areas: Polycystic Ovary Syndrome (PCOS)- related symptoms, Hirsutism, Menorrhagia, Urinary Tract Infections (UTI), Pre Menstrual Syndrome (PMS), Menopause symptoms management, Vaginal health, sarcopenia, Sexual drive (libido & orgasm), Ovary volume, Vulvovaginal candidiasis.
Tools: Nugent score, Quality of life Questionnaires like SF-36, Bond Lader, Green Climacteric Scale, Lean body mass index The Daily Record of Severity of Problems (DRSP), Premenstrual Symptoms Screening Tool (PSST), diagnostic and statistical manual for mental disorders (DSM-5), Shortened Premenstrual Assessment Form, Beck Depression, modified Ferriman Gallway score, Rosenberg Self-Esteem Scale, and Kessler psychological distress scale, abdominopelvic ultrasound, Doppler, Urinary Tract Infection Symptoms Assessment Questionnaire (UTISA), Duration of UTI symptoms, No. of UTI episodes.
Biomarkers: Dehydroepiandrosterone Sulfate (DHEAS), FSH LH levels, Hormone profiling (Estrogen, Progesterone Levels), Free testosterone levels in blood, Urine culture, PAP Smear, Vaginal pH, Vaginal microbiota analysis, FBI, Lipid profile, AMH levels, serum Sex Hormone Binding Globulin (SHBG) concentrations
Beauty from Within (Skin Health)
Trending claim areas: Skin Hydration & moisture, Improvement in Wrinkle severity & Skin elasticity, Acne Vulgaris, pigmentation, Anti-pollution, anti-oxidants, wound healing, Skin collagen booster, Sebum Secretion, skin inflammation, Healthy Aging.
Tools: Radiance & Moisturization Analysis, Wrinkle analysis, Patch testing, Trans Epidermal Water Loss (TEWL), Modified Fitzpatrick Wrinkle Severity Scale (MFWS), pinch recoil test, Global Acne Grading System, Dermatology Life Quality Index (DLQI), Sebometer. Antera 3 D, Sphectrophotometer
Biomarkers: IgE (Immunoglobin E), eosinophils, serum lactate dehydrogenase, serum levels of lipocalin-2, Retinol-binding protein 4 (RBP4), facial fat content
