A Hong Kong-based manufacturer of complementary medicine based on TCM approached Vedic Lifesciences for research on an adhesive patch called Patch-It®. They were commercializing this medical device in the UK, US, and Asia for swelling, aching and discomfort in the lower limbs. They needed a formal study to substantiate their claims to their target audience as well as regulatory. A total of 100 patients with recurring swelling in the feet were randomized in this placebo-controlled multi-centric study. Patches were applied to both soles overnight for 8 weeks. Patch-It® was more effective than the placebo in alleviating recurring swelling and aching in the legs and feet.