Vedic Lifesciences

Efficacy and dose response of Lactiplantibacillus plantarum in diarrhea-predominant irritable bowel syndrome

This is a prospective, randomized, double-blind, placebo-controlled, multi-center, and parallel-arm study, including two doses of the probiotic product and one placebo arm. The study investigated the clinical efficacy of Lactiplantibacillus plantarum Lpla33 in adults with IBS-D. A total of 333 screened participants were assessed for eligibility and 314 participants were randomized in the study. Three hundred and seven adults, 18-70 years of age, both male and female with IBS-D were allocated the (1:1:1) procedure.

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